BDBM501772 4-[6-(4-aminopiperidin-1-yl)-4- [(3-methoxyphenyl)methyl]-5- oxo-4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 10
SMILES COc1cccc(Cn2cc(nc(N3CCC(N)CC3)c2=O)-c2ccc(cc2)C#N)c1
InChI Key InChIKey=KBQUVRLOHDHKNV-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501772
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair